ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Hydration of osmolites
Abstract: Knowledge of the hydration of small osmolytes can challenge the "preferential exclusion" model hypothesized to explain their action as bio-protectant against osmotic stress. This model is based on the assumption that osmolyte-water interactions are stronger than osmolyte-osmolyte ones. Available neutron diffraction data on aqueous solutions of other osmolytes (as glycine and proline) and of sugars (as trehalose) do not seem to confirm this interpretation. In order to gain better knowledge of the balance solute-solute and solute-solvent interactions at the atomistic level in this class of small bio-molecules, we propose to perform NDIS experiments on aqueous solutions of ectoine and trimethylglycine. The former has been chosen in order to compare with the recent SANS results, the latter because it has much weaker solute-solute interactions than glycine.
Principal Investigator: Professor Maria Antonietta Ricci
Experimenter: Dr Silvia Imberti
Experimenter: Professor Fabio Bruni
DOI: 10.5286/ISIS.E.RB1710038
ISIS Experiment Number: RB1710038
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.87768503 | SANDALS | 28 May 2020 | Download |
| 10.5286/ISIS.E.87768521 | SANDALS | 02 October 2020 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Maria Antonietta Ricci et al; (2017): Hydration of osmolites, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1710038
Data is released under the CC-BY-4.0 license.
