ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
SANS evaluation of novel nanocolloidal drug carriers
Abstract: With the beamtime requested we plan to employ small-angle neutron scattering (SANS) to study novel nanocolloidal drug carriers prepared using lipids, surfactants and co-surfactants. These can address solubility, stability and bioavailability issues of drugs. SANS will be used to monitor:• Size/thickness of surfactant layer of developed systems.• Orientation/ spatial arrangement of components viz. surfactant, co-surfactant and surfactant supporting agents around the lipid core or in the vesicles.• Existence of other structures viz. micelles, supercooled melts or nanostructured lipid carriers.• Particle aggregation.• Particle-particle interactions.• Mesophase or smectic nature of the systems.Systems are aqueous nanodispersions and D2O will be used for neutron contrast. 25 & 37 ◦C, will be used to study changes and amorphous/crystalline nature.
Principal Investigator: Professor Indu Pal Kaur
Experimenter: Ms Simarjot Kaur Sandhu
Experimenter: Dr Sarah Rogers
Experimenter: Mr Mandeep Singh
DOI: 10.5286/ISIS.E.RB1768044
ISIS Experiment Number: RB1768044
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.87774665 | SANS2D | 04 October 2020 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Indu Pal Kaur et al; (2017): SANS evaluation of novel nanocolloidal drug carriers, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1768044
Data is released under the CC-BY-4.0 license.
