ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.


The role of chirality on polymeric membrane lytic activity

Abstract: The human body has a well developed membrane chemistry which allows transport of fluids and salts whilst preventing other molecules and harmful agents from penetrating the cell. Transport of drugs and other benefit agents relies on developing agents which behave like the constituents of the cell membrane but then release their payload on entering the cell. The aim of this proposal is to establish how modifying the chemistry of a copolymer which forms tubes at a high pH can be manipulated to give the appropriate degree of pH response in order to ultimately develop a suitable delivery system.

Principal Investigator: Dr Ian Tucker
Experimenter: Mr Alexander Chen
Experimenter: Professor Nigel Slater
Experimenter: Dr Rongjun Chen
Experimenter: Dr Radka Petkova
Local Contact: Dr Robert Dalgliesh

DOI: 10.5286/ISIS.E.RB1710247

ISIS Experiment Number: RB1710247

Part DOI Instrument Public release date Download Link
10.5286/ISIS.E.84801788 LARMOR 10 March 2020 Download

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Ian Tucker et al; (2017): The role of chirality on polymeric membrane lytic activity, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1710247

Data is released under the CC-BY-4.0 license.



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