ISIS Neutron and Muon Source Data Journal

Cryopreservation of liver transplant cells

Abstract: Development of new cryopreservation strategies has major potential in medicine and agriculture, and is critical to the conservation of endangered species that currently cannot be preserved. Recently we have applied for IRIS Express 1690294 to study cryopreserved alginate-encapsulated liver cell spheroids used in artificial liver bio-transplant using high-resolution QENS spectroscopy. The results of the IRIS Express QUENS measurement have shown visible difference between the sample prepared according to cryopreservation temperature protocol and the same sample but quench cooled in liquid Nitrogen. In order to reproduce and obtain a higher quality data we propose QENS measurements of cryopreserved alginate-encapsulated liver cell spheroids sample in temperature range 80 – 350K. These data could allow us to understand better the processes that happen in this biological system.

Principal Investigator: Professor Barry Fuller
Experimenter: Dr Ian Silverwood
Experimenter: Dr Oleg Kirichek
Experimenter: Dr Victoria Garcia Sakai
Experimenter: Mr Maooz Awan

DOI: 10.5286/ISIS.E.RB1710165

ISIS Experiment Number: RB1710165

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Barry Fuller et al; (2017): Cryopreservation of liver transplant cells, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1710165

Data is released under the CC-BY-4.0 license.