ISIS Neutron and Muon Source Data Journal

Protein-decorated superparamagnetic iron oxide nanoparticles

Abstract: The aim of this research is to understand the structural confirmation of dextran coated iron oxide (Fe3O4) nanoparticles in the presence of Bovine serum albumin (BSA) in aqueous solution; the effects of the dextran coating shall be investigated over a range of pH values and BSA concentrations. The experiment seeks to explore the nature of the interactions between BSA and the coated NPs, and to verify whether, the BSA forms a secondary shell or competes with the dextran for the NP surface. Preliminary SANS (Figure 1) and light scattering measurements indicate that the structure of the aggregates is unchanged upon addition of BSA, however, the size of the aggregates increased. This project is supported by the Welsh Government Sêr Cymru programme and the National Research Network (Wales).

Principal Investigator: Dr Shirin Alexander
Local Contact: Dr Sarah Rogers
Experimenter: Mr Jefferson de Oliveira Mallia
Experimenter: Dr Virginia Gomez Jimenez
Experimenter: Dr Dan Jones

DOI: 10.5286/ISIS.E.RB1700023

ISIS Experiment Number: RB1700023

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Shirin Alexander et al; (2017): Protein-decorated superparamagnetic iron oxide nanoparticles, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1700023

Data is released under the CC-BY-4.0 license.