ISIS Neutron and Muon Source Data Journal

The use of lipid sponge-like nanoparticles as carriers for macromolecules and their interaction with proteins

Abstract: Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be developed for active compounds that are large, like proteins, or that cannot be dissolved in water. One of the proposed methods is the use of lipid based nanoparticles. Lipids are very abundant in the nature; we eat them, we process or digest them and even our cell membranes are formed by lipids. They have the advantage that can organize themselves in different structures depending on the nature of the lipid and its environment. Therefore, these particles are a potential tool for the encapsulation and control release of macromolecules. In addition, lipid based nanoparticles can also be of benefit in the food industry. For example, they can be used to control the delivery of enzymes employed during food processing.

Principal Investigator: Professor Tommy Nylander
Local Contact: Dr Rebecca Welbourn
Local Contact: Dr Maxmilian Skoda
Experimenter: Ms Polina Naidjonoka
Experimenter: Ms Maria Valldeperas Badell
Experimenter: Dr Justas Barauskas

DOI: 10.5286/ISIS.E.RB1710262

ISIS Experiment Number: RB1710262

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Tommy Nylander et al; (2017): The use of lipid sponge-like nanoparticles as carriers for macromolecules and their interaction with proteins, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1710262

Data is released under the CC-BY-4.0 license.