ISIS Neutron and Muon Source Data Journal

Rheo-SANS of folded maltose binding protein hydrogels

Abstract: Hydrogels are formed by the self-assembly of cross-linked building blocks in water.By using a folded protein as the building block, we wish to harness the intrinsic and specific mechanical properties of the individual folded proteins. We propose to use Rheo-SANS on the instrument SANS2d to investigate theeffect of stress on the architecture of hydrogels made using folded, globular maltose binding proteins. Our aim is to gain insight into the connection between the structure of the hydrogel network and its mechanical properties. This new information is crucial in building up a cross length scale understanding of the mechanical properties of a protein hydrogel, and will allow us to determine design parameters (specifically cross-link density and location on protein). This will allow the development of novel hydrogels which will have great potential in healthcare applications.

Principal Investigator: Professor Lorna Dougan
Experimenter: Dr Harrison Laurent
Experimenter: Miss Sophie Cussons
Local Contact: Dr Najet Mahmoudi
Experimenter: Dr Matthew Hughes

DOI: 10.5286/ISIS.E.RB1820510

ISIS Experiment Number: RB1820510

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Lorna Dougan et al; (2018): Rheo-SANS of folded maltose binding protein hydrogels, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1820510

Data is released under the CC-BY-4.0 license.