ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.


Substrate-dependent structure of thin hydrogel films

Abstract: Hydrogels are water-rich polymer networks made from natural or synthetic polymers, which are widely used in biomaterials, medicine and antifouling. We have developed PEG-based hydrogels which are grafted through UV-initiated free-radical polymerization, suitable for use in biosensing applications since they have low non-specific protein adsorption and permit controlled modification by ligands. The processing can be tuned to produce a given polymer mass per surface area, but growth rates vary between substrate types, and is 2-4 times faster on gold than on silicon; two substrate types which are important for biosensors. We will investigate how this affects the structure of the swollen hydrogels. The low polymer/water contrast in the wet polymer makes structural characterization difficult, but via H-D-substitution, neutron reflectometry can be used to determine the swelling and density.

Principal Investigator: Dr Thomas Ederth
Local Contact: Dr Jos Cooper
Experimenter: Dr Bela Nagy

DOI: 10.5286/ISIS.E.RB1820546

ISIS Experiment Number: RB1820546

Part DOI Instrument Public release date Download Link
10.5286/ISIS.E.99691448 OFFSPEC 10 February 2022 Download

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Thomas Ederth et al; (2018): Substrate-dependent structure of thin hydrogel films, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1820546

Data is released under the CC-BY-4.0 license.



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