ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides
Abstract: Neutron reflection (NR) is well established for studying molecular films such as lipid monolayers. Its high depth resolution combined with deuterium labelling can determine the amount and location of binding of antimicrobial peptides (AMPs). By unravelling how AMPs interact with model lipopolysaccharide (LPS) membranes NR can help us to develop strain-specific AMPs to target at Gram-negative bacteria whilst tuning their biocompatibility to mammalian cell hosts. we request 3 days on INTER or 4 days of Surf to complete this work. Inter is preferred due to weak but measurable signals from h-lipid-h-peptide in NRW.
Principal Investigator: Professor Jian Lu
Experimenter: Dr Mingrui Liao
Experimenter: Mr KE FA
Experimenter: Dr Zongyi Li
Experimenter: Mr Haoning Gong
Experimenter: Dr Luke Clifton
Local Contact: Dr Mario Campana
Experimenter: Miss Daniela Ciumac
Experimenter: Mr Peter Hollowell
DOI: 10.5286/ISIS.E.RB1820088
ISIS Experiment Number: RB1820088
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.98001371 | SURF | 04 October 2021 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
Select the data format above to find
out more about it.
Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2018): Lipopolysaccharide Functions as Bacterial Receptors to Antimicrobial Peptides, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1820088
Data is released under the CC-BY-4.0 license.
