ISIS Neutron and Muon Source Data Journal

Lipid exchange dynamics between native lipoprotein particles and human cell mimics – Increasing the complexity of the cell membrane

Abstract: Atherosclerosis is the primary cause of death in westernized societies. Clinical indicators include not only the net lipoprotein concentration but also the ratio between the various lipoprotein particles such as low density lipoproteins (LDL) and high density lipoproteins (HDL). Many different factors are thought to affect their structure and the way they interact with the various vessel wall components. Understanding the initial events leading to atherosclerosis is the main focus of our group. Using neutron scattering techniques we are currently unraveling the lipoprotein ability to unload their lipid cargo and how this relates to their structure/composition relationship by monitoring the changes that occur upon native lipoprotein interactions with mimics of the blood vessel wall.

Principal Investigator: Professor Marité Cárdenas Gómez
Experimenter: Miss Sarah Waldie
Experimenter: Dr Selma Maric
Experimenter: Mr Rami Iskif
Local Contact: Dr Sarah Rogers
Experimenter: Dr Dainius Jakubauskas
Experimenter: Mr Nico Koenig

DOI: 10.5286/ISIS.E.RB1810447

ISIS Experiment Number: RB1810447

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Marité Cárdenas Gómez et al; (2018): Lipid exchange dynamics between native lipoprotein particles and human cell mimics – Increasing the complexity of the cell membrane, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1810447

Data is released under the CC-BY-4.0 license.