ISIS Neutron and Muon Source Data Journal

Effect of emulsifier and added preservative on the structure and stability of model skin care creams

Abstract: Investigations will be performed to determine the effect of composition on the internal structure of semi-solid oil-in-water emulsions designed to model the GlaxoSmithKline Physiogel range of skin care products. The model creams studied will involve essential structural components only, viz., chemically pure surfactant/co-surfactant emulsifier, and water, but with added (hydrogen- or deuterium-labelled) preservative. The latter is added to prevent microbial contamination of the creams but is also found to cause detrimental changes in long-term stability. The studies will be performed on systems with varying emulsifier composition, prepared with and without preservative, both fresh and after 1-month's storage. By such means, we aim to determine the changes in structure that manifest over time due to changes in emulsifier composition, and also those due to addition of preservative.

Principal Investigator: Dr Dave Barlow
Experimenter: Dr Fabrizia Foglia
Experimenter: Professor Jayne Lawrence
Experimenter: Dr Delaram Ahmadi
Experimenter: Dr Gillian Eccleston
Local Contact: Dr Najet Mahmoudi

DOI: 10.5286/ISIS.E.RB1800007

ISIS Experiment Number: RB1800007

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Dave Barlow et al; (2017): Effect of emulsifier and added preservative on the structure and stability of model skin care creams, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1800007

Data is released under the CC-BY-4.0 license.