ISIS Neutron and Muon Source Data Journal

Biological membrane mimics made of deuterated lipids extracted from E. coli

Abstract: Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular membranes is imperative in order to advance the understanding of for example their role as barriers and for affinity studies with biomolecules in solution. Recently, there has been a boost in the development of complex membranes for models of bacterial membranes among others. In this work we would like to further contribute at the advancing of this field by creating mimics of mammalian membranes using deuterated lipid species extracted from various strains of E. coli: a genetically modified strain that produces PC and regular strains producing PE, PG and cardiolipin.

Principal Investigator: Professor Marité Cárdenas Gómez
Local Contact: Dr Nina-Juliane Steinke
Experimenter: Dr Selma Maric
Experimenter: Dr Tania Lind
Experimenter: Dr Kathryn Browning
Local Contact: Dr Maxmilian Skoda
Experimenter: Miss Josefine Eilsø Nielsen
Experimenter: Miss Sarah Waldie
Local Contact: Dr Rebecca Welbourn

DOI: 10.5286/ISIS.E.RB1610193

ISIS Experiment Number: RB1610193

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Professor Marité Cárdenas Gómez et al; (2017): Biological membrane mimics made of deuterated lipids extracted from E. coli, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1610193

Data is released under the CC-BY-4.0 license.