ISIS Neutron and Muon Source Data Journal

Novel dual purpose antimicrobials and co-formulates to regenerate currently redundant antimicrobials

Abstract: The increased prevalence of antimicrobial resistant bacteria is the most significant challenge facing the human-health today in both developed and developing worlds. It's estimated that by the year 2050 antimicrobial resistant bacterial infections will be responsible for more deaths each year than cancer. The identification of novel antimicrobials is therefore a major priority. The proposers are currently investigating Supramolecular Self-associating Amphiphiles (SSAs) as a novel class of antimicrobial and co-formulate which have the potential to achieve these global objectives (Patent Application No. PCT/EP2018/069568). Within the scope of this proposal we wish to investigate the interaction of one such candidate SSA with a number of model membrane to elucidate the interaction mechanism providing invaluable information as to their mode of action to help optimise future synthetic design.

Principal Investigator: Dr Jen Hiscock
Experimenter: Dr Rob Barker
Local Contact: Dr Mario Campana
Experimenter: Miss Chloe Marie Skingle
Experimenter: Miss Irantzu Yoldi

DOI: 10.5286/ISIS.E.RB1910537

ISIS Experiment Number: RB1910537

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
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Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Jen Hiscock et al; (2019): Novel dual purpose antimicrobials and co-formulates to regenerate currently redundant antimicrobials, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1910537

Data is released under the CC-BY-4.0 license.