ISIS Neutron and Muon Source Data Journal

Investigation of lipid head group dependent adhesion of membrane proteins using neutron reflectivity study

Abstract: The lipid membranes and their interactions with the integral or peripheral proteins serve as one of the key mechanism in various cellular functions like communication, cell defences, signal transduction etc. The lipid membranes not only protects the cells but also acts as filter or switchable gate way, controlling the flow of nutrients into and metabolic wastes out of the cells. It is predicted that the relative organization of the constituent bio-molecules and their preferential attachment with the proteins control various physical parameters like surface tension, stretching and bending elasticity, viscosity of the membrane subsequently helping the cell functions. In this proposed experiment we will be investigating the attachment mechanism and the preferential orientation of flexible and non-flexible polymer like proteins with the different lipids headgroups using neutron reflectivity.

Principal Investigator: Dr Mrinmay Kumar Mukhopadhyay
Experimenter: Professor Milan Sanyal
Local Contact: Dr Maxmilian Skoda
Experimenter: Professor Abhijit Chakrabarti

DOI: 10.5286/ISIS.E.RB1868032

ISIS Experiment Number: RB1868032

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Mrinmay Kumar Mukhopadhyay et al; (2019): Investigation of lipid head group dependent adhesion of membrane proteins using neutron reflectivity study, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1868032

Data is released under the CC-BY-4.0 license.