ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane Leaflets of Microorganisms by Neutron Reflection
Abstract: Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with different hydrophobicity. The use of partially deuterated peptides and lipids will help improve interfacial structure resolution. We hypothesize that their different structural features implicate how they interact with bacterial membranes and kill them. NR is the only technique that can determine the amount and distribution of these represent AMPs once bound. We request 4 days on Surf to complete this work.
Principal Investigator: Professor Jian Lu
Local Contact: Dr Mario Campana
Experimenter: Mr KE FA
Experimenter: Mr Haoning Gong
Experimenter: Dr Zongyi Li
Experimenter: Mr Huayang Liu
Experimenter: Mr Peter Hollowell
DOI: 10.5286/ISIS.E.RB1910071
ISIS Experiment Number: RB1910071
| Part DOI | Instrument | Public release date | Download Link |
|---|---|---|---|
| 10.5286/ISIS.E.101140102 | SURF | 06 March 2022 | Download |
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2019): Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane Leaflets of Microorganisms by Neutron Reflection, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1910071
Data is released under the CC-BY-4.0 license.
