ISIS Neutron and Muon Source Data Journal

This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.

ISIS Neutron and Muon Source

ISIS Neutron and Muon Data

Structural and mechanistic study of nanocapsule / hydrogel composites for drug delivery applications

Data collected on the
SANS2D instrument
at the ISIS facility

Abstract: The targeted delivery of non-water soluble drugs for applications such as cancer remains a major challenge. Nanocapsules are new materials that can act as a depot for such drugs and release them in a controlled manner; however, they are difficult to keep in the location where drug delivery is desired. We are exploring the use of a fibrillar network, a self-assembled hydrogel, as promising means to act as a depot for the nanocapsules. While the hydrogel itself cannot control the release of the drug, it is able to 'trap' the nanocapsules and keep them at the site of action.While promising, this approach is relatively new and little is known about the interactions between nanocapsule and the hydrogel fibres. This work aims to gain critical insight into these interactions essential to the ability to design the composite material for optimised stability and drug delivery performance

Public release date: 18 June 2021

Principal Investigator: Dr Mischa Zelzer
Experimenter: Mr Bhanu Teja Surikutchi
Experimenter: Dr Bin Yang
Experimenter: Professor Maria Alonso
Experimenter: Dr Najet Mahmoudi
Experimenter: Dr Maria Marlow
Experimenter: Miss Maria Angelerou
Experimenter: Miss maria galini faidra angelerou

DOI: 10.5286/ISIS.E.95670534

Parent DOI: 10.5286/ISIS.E.RB1810489

ISIS Experiment Number: RB1810489

Part Number: 1

download
the dataset

Date of Experiment: 15 June 2018

Publisher: STFC ISIS Neutron and Muon Source

Data format: RAW/Nexus
Select the data format above to find out more about it.

Data Citation

The recommended format for citing this dataset in a research publication is as:
[author], [date], [title], [publisher], [doi]

For Example:
Dr Mischa Zelzer et al; (2018): Structural and mechanistic study of nanocapsule / hydrogel composites for drug delivery applications, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.95670534

Data is released under the CC-BY-4.0 license.