ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Development of interfacial models to understand preservation through neutron reflection
Abstract: The aim of this project is to understand how such surface-active preservative actives work and how additional surface-active molecules could help boost their biocidal efficacy. This project is part of our ongoing collaboration to apply neutron and X-ray techniques to improve our understanding of antimicrobial efficacy and dynamic killing, however it will be the first to explore preservative actives. Neutron reflection is about the only technique that can help unravel structural information at the molecular and membrane levels about how preservatives interact with microbial membranes, with and without booster molecules. Model lipid membrane systems will be developed to aid the determination of the structure and composition of the interfacial films when the boosters, bioactive and their representative mixtures interact with the lipid models mimicking different microbial membranes. This work should require 3 days of beam time.
Public release date: 18 December 2027
Principal Investigator: Ms Kate Alston
Experimenter: Professor Jian Lu
Experimenter: Dr Peixun Li
Local Contact: Dr Maxmilian Skoda
Experimenter: Miss Tianhao Ge
Experimenter: Professor Jordan Petkov
Experimenter: Miss Yingyu Wang
Local Contact: Dr John Webster
DOI: 10.5286/ISIS.E.RB2410396-2
Parent DOI: 10.5286/ISIS.E.RB2410396
ISIS Experiment Number: RB2410396
Part Number: 2
This dataset is NOT yet publicly available.
The release date is: 18 December 2027
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Date of Experiment: 13 December 2024
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Ms Kate Alston et al; (2024): Development of interfacial models to understand preservation through neutron reflection, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2410396-2
Data is released under the CC-BY-4.0 license.
