ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Characterising XopR during membrane interactions
Abstract: The role of Liquid-liquid phase separation (LLPS) in biology is increasingly recognised. Actin remodelling has been found to involve LLPS, which likely acts to upregulate critical proteins and adjust their activity. Intrinsically disordered protein XopR, which undergoes LLPS at a pH of 7.4, has been found to trigger actin remodelling. Previous NR work performed at ISIS and ANSTO have shown the effect of XoPR on a variety of dueterated lipid membranes in both LLPS and dilute conditions. Here, neutron reflectometry will be used with dueterated XopR to isolated the structrue of XopR on the surface of the membrane.
Public release date: 26 November 2027
Principal Investigator: Professor Marité Cárdenas Gómez
Experimenter: Dr Claire Buchanan
Local Contact: Dr Oleksandr Tomchuk
Experimenter: Mr Jon Altuna
Experimenter: Ms Soto Noelia
DOI: 10.5286/ISIS.E.RB2420136-1
Parent DOI: 10.5286/ISIS.E.RB2420136
ISIS Experiment Number: RB2420136
Part Number: 1
This dataset is NOT yet publicly available.
The release date is: 26 November 2027
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Date of Experiment: 20 November 2024
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Marité Cárdenas Gómez et al; (2024): Characterising XopR during membrane interactions, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2420136-1
Data is released under the CC-BY-4.0 license.
