ISIS Neutron and Muon Source Data Journal
This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Interactions between Cell Mimicking Vesicles and de novo Ultrashort Peptide Amphiphiles: A Comparative SANS Study
Abstract: In this work, we propose to exploit the unique capability of SANS to study the structural changes of the multi-component lipid bilayers surrounding small unilamellar vesicles (SUVs). SUVs of different lipid composition work well as models mimicking bacterial and mammalian cell membranes. Upon exposure to de novo designed ultrashort antimicrobial lipopeptides, SANS helps unravel how different lipopeptides bind to different lipid bilayers, providing useful indications about different mechanisms of action. We request 2 days on SANS2d time to exploit its wide Q range for resolving different sizes of structures and high flux for following dynamic structural changes.
Public release date: 26 November 2023
Principal Investigator: Professor Jian Lu
Experimenter: Mr Sean Ruane
Experimenter: Mr KE FA
Local Contact: Dr Robert Dalgliesh
Experimenter: Dr Zongyi Li
DOI: 10.5286/ISIS.E.RB2010128-1
Parent DOI: 10.5286/ISIS.E.RB2010128
ISIS Experiment Number: RB2010128
Part Number: 1
Date of Experiment: 23 November 2020
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2020): Interactions between Cell Mimicking Vesicles and de novo Ultrashort Peptide Amphiphiles: A Comparative SANS Study, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB2010128-1
Data is released under the CC-BY-4.0 license.
